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Protein engineering of antibody fragments for pharmaceutical production

2023-09-01

Abstract excerpt

Antibody fragments without the Fc region are attracting attention in the pharmaceutical industry due to their high ability to penetrate solid tissues, cost-effective expression using microbial expression systems, and distinctive modes of action compared to those of full-size antibodies. Based on these characteristics, several antibody fragment agents have been approved. However, developing platform engineering met...

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Literature Corpus work
79689a3b-5bc9-5d87-a2e4-635c3334a076
DOI
10.1063/5.0158032
Open publication

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