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Update on Fc receptor-like (FCRL) family: new immunoregulatory players in health and diseases

8 May 2018

Abstract excerpt

INTRODUCTION: Fc receptor-like (FCRL) molecules, as recently identified members of the immunoglobulin superfamily (IgSF), are preferentially expressed by B-cells. They have variable number of extracellular immunoglobulin-like domains and cytoplasmic activating ITAMs and/or inhibitory ITIMs. FCRL1-5 are dominantly expressed in different stages of B-cells development. But, FCRL6 is preferentially expressed in...

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PMID: 29737217
DOI: 10.1080/14728222.2018.1472768

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