Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of PICALM with Cognitive Impairment in Parkinson's Disease.

Movement disorders : official journal of the Movement Disorder Society - 1 Jan 2021

Periñán María Teresa, Macías-García Daniel, Labrador-Espinosa Miguel Ángel, Jesús Silvia, Buiza-Rueda Dolores, Adarmes-Gómez Astrid D, Muñoz-Delgado Laura, Gómez-Garre Pilar, Mir Pablo

Abstract excerpt

BACKGROUND: Cognitive impairment is one of the most disabling nonmotor symptoms in Parkinson's disease (PD). Recently, a genome-wide association study in Alzheimer's disease has identified the PICALM rs3851179 polymorphism as one of the most significant susceptibility genes for Alzheimer's disease after APOE. The aim of this study was to determine the potential role of PICALM and its genetic interaction with APOE...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cognitive Dysfunction

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Monomeric Clathrin Assembly Proteins

Share to Parkinson Disease

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 32914893
DOI: 10.1002/mds.28283

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of PICALM with Cognitive Impairment in Parkinson's Disease.PMID 32914893Read ↗

Investigation of Genetic Variants Associated with Alzheimer Disease in Parkinson Disease Cognition.Semantic proximity Read ↗

CLU rs11136000 promotes early cognitive decline in Parkinson's disease.Semantic proximity Read ↗

GBA and APOE Impact Cognitive Decline in Parkinson's Disease: A 10-Year Population-Based Study.Semantic proximity Read ↗

Association of Alzheimer's disease risk variants on the PICALM gene with PICALM expression, core biomarkers, and feature neurodegeneration.Semantic proximity Read ↗

Genome‐Wide Association Studies of Cognitive and Motor Progression in Parkinson's DiseaseSemantic proximity Read ↗

Cognitive impairment in Parkinson's disease.Semantic proximity Read ↗

Large-scale exploratory genetic analysis of cognitive impairment in Parkinson's disease.Semantic proximity Read ↗

Identification of susceptibility loci for cognitive impairment in a cohort of Han Chinese patients with Parkinson's disease.Semantic proximity Read ↗

APOE, MAPT, and COMT and Parkinson's Disease Susceptibility and Cognitive Symptom Progression.Semantic proximity Read ↗

APOE, MAPT, and SNCA genes and cognitive performance in Parkinson disease.Semantic proximity Read ↗

GWAS Identifies DPP6 as Risk Gene of Cognitive Decline in Parkinson's Disease.Semantic proximity Read ↗

Genetic factors influencing frontostriatal dysfunction and the development of dementia in Parkinson's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.