Article
Large-scale exploratory genetic analysis of cognitive impairment in Parkinson's disease.
Neurobiology of aging - 1 Aug 2017
Mata Ignacio F, Johnson Catherine O, Leverenz James B, Weintraub Daniel, Trojanowski John Q, Van Deerlin Vivianna M, Ritz Beate, Rausch Rebecca, Factor Stewart A, Wood-Siverio Cathy, Quinn Joseph F, Chung Kathryn A, Peterson-Hiller Amie L, Espay Alberto J, Revilla Fredy J, Devoto Johnna, Yearout Dora, Hu Shu-Ching, Cholerton Brenna A, Montine Thomas J, Edwards Karen L, Zabetian Cyrus P
Abstract excerpt
Cognitive impairment is a common and disabling problem in Parkinson's disease (PD). Identification of genetic variants that influence the presence or severity of cognitive deficits in PD might provide a clearer understanding of the pathophysiology underlying this important nonmotor feature. We genotyped 1105 PD patients from the PD Cognitive Genetics Consortium for 249,336 variants using the NeuroX array....
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