Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Abundance of Noncircular Intrahepatic Hepatitis B Virus DNA May Reflect Frequent Integration Into Human DNA in Chronically Infected Patients

8 Sept 2020

Abstract excerpt

BACKGROUND: Hepatitis B virus (HBV) integration has implications for cancer development and surface antigen (HBsAg) production, but methods to quantify integrations are lacking. The aim of this study was to develop a droplet digital PCR (ddPCR) assay discriminating between circular and integrated HBV DNA, and to relate the distribution between the two forms to other HBV markers. METHODS: ddPCR with primers...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hepatitis B Virus Studies
Share to HIV Research and Treatment
Share to RNA Interference and Gene Delivery

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32910825
DOI: 10.1093/infdis/jiaa572

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Abundance of Noncircular Intrahepatic Hepatitis B Virus DNA May Reflect Frequent Integration Into Human DNA in Chronically Infected PatientsPMID 32910825Read ↗

Whole exome HBV DNA integration is independent of the intrahepatic HBV reservoir in HBeAg-negative chronic hepatitis B.Semantic proximity Read ↗

Hepatitis B Virus RNA Profiles in Liver Biopsies by Digital Polymerase Chain ReactionSemantic proximity Read ↗

HBV-Integration Studies in the Clinic: Role in the Natural History of InfectionSemantic proximity Read ↗

Hepatitis B Virus DNA Integration: In Vitro Models for Investigating Viral Pathogenesis and PersistenceSemantic proximity Read ↗

Hepatitis B Virus DNA Integration, Chronic Infections and Hepatocellular CarcinomaSemantic proximity Read ↗

Cellular Genomic Sites of Hepatitis B Virus DNA IntegrationSemantic proximity Read ↗

Hepatitis B virus DNA integration as a novel biomarker of hepatitis B virus-mediated pathogenetic properties and a barrier to the current strategies for hepatitis B virus cureSemantic proximity Read ↗

Insights into Hepatitis B Virus DNA Integration-55 Years after Virus DiscoverySemantic proximity Read ↗

Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus ParticlesSemantic proximity Read ↗

Role of hepatitis B virus DNA integration in human hepatocarcinogenesis.Semantic proximity Read ↗

HBV DNA Integration: Molecular Mechanisms and Clinical ImplicationsSemantic proximity Read ↗

Among Patients with Undetectable Hepatitis B Surface Antigen and Hepatocellular Carcinoma, a High Proportion Has Integration of HBV DNA into Hepatocyte DNA and No CirrhosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.