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Article

Characterization of Novel Cross-Reactive Influenza B Virus Hemagglutinin Head Specific Antibodies That Lack Hemagglutination Inhibition Activity.

Journal of virology - 9 Nov 2020

Kirkpatrick Ericka, Henry Carole, McMahon Meagan, Jiang Kaijun, Strohmeier Shirin, van Bakel Harm, Wilson Patrick C, Krammer Florian

Abstract excerpt

Humoral immune responses to influenza virus vaccines in elderly individuals are poorly adapted toward new antigenically drifted influenza virus strains. Instead, older individuals respond in an original antigenic sin fashion and produce much more cross-reactive but less potent antibodies. Here, we investigated four influenza B virus hemagglutinin (HA) head specific, hemagglutination inhibition-inactive monoclonal...

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Source

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Identifiers

PMID: 32907980
DOI: 10.1128/JVI.01185-20
PMCID: PMC7654279

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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