Article
The risk of anti-osteoporotic agent-induced severe cutaneous adverse drug reactions and their association with HLA.
Journal of the European Academy of Dermatology and Venereology : JEADV - 1 Mar 2021
Chen C-B, Chen Y-E, Chu M-T, Wang C-W, Hui R C-Y, Lu C-W, Hsiao Y-P, Chu C-Y, Chang M M, Cheung C M-T, Cheng C-Y, Wang Y-W, Lin Y-J, Chang C-J, Hung S-I, Chung W-H
Abstract excerpt
BACKGROUND: There is increasing use of anti-osteoporotic agents (AOA) worldwide for prevention or management of patients with osteoporosis. However, there have been reports of severe cutaneous adverse reactions (SCAR) induced by AOA. A recent study showed weak association between HLA and strontium ranelate (SR)-SCAR. OBJECTIVE: To characterize patients with AOA-SCAR and investigate the HLA association and utility...
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