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Severe Cutaneous Adverse Reactions: The Pharmacogenomics from Research to Clinical Implementation

15 Nov 2016

Abstract excerpt

Severe cutaneous adverse reactions (SCARs), previously thought to be idiosyncratic or unpredictable, are a deadly form of adverse drug reactions with skin manifestations. Current pharmacogenomic studies of SCARs have made important strides, as the prevention of SCARs, to some extent, appears attainable with the identification of genetic variants for genes encoding drug-metabolizing enzymes and human leukocyte...

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PMID: 27854302
DOI: 10.3390/ijms17111890

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