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The roles of carbonic anhydrases IX and XII in cancer cell adhesion, migration, invasion and metastasis

21 Sept 2020

Abstract excerpt

. However, the data of in vitro and in vivo studies have demonstrated that transmembrane isoforms of CA IX and CA XII are involved in various steps of cancer cell migration, invasion and metastasis. According to literature, inhibition of these CAs can affect the expression of multiple proteins. Some scientific groups have reported the possible interactions between CA IX and E-cadherin-catenin system, CA IX and...

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PMID: 32894882
DOI: 10.1111/boc.201900099

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