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Article

Carbonic anhydrase related protein VIII and its role in neurodegeneration and cancer.

Current pharmaceutical design - 1 Jan 2010

Aspatwar Ashok, Tolvanen Martti E E, Ortutay Csaba, Parkkila Seppo

Abstract excerpt

Mammalian carbonic anhydrase (α-CA) gene family comprises sixteen isoforms, thirteen of which are active isozymes and three isoforms lack classical CA activity of reversible hydration of CO(2) due to absence of one or more histidine residues required for CA catalytic activity. The inactive isoforms are known as carbonic anhydrase related proteins (CARPs) VIII, X and XI. Among these three, CARP VIII was reported...

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Identifiers

PMID: 20819067
DOI: 10.2174/138161210793429823

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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