Article
Expression of a novel carbonic anhydrase, CA XIII, in normal and neoplastic colorectal mucosa.
BMC cancer - 18 Apr 2005
Kummola Laura, Hämäläinen Jonna M, Kivelä Jyrki, Kivelä Antti J, Saarnio Juha, Karttunen Tuomo, Parkkila Seppo
Abstract excerpt
BACKGROUND: Carbonic anhydrase (CA) isozymes may have an important role in cancer development. Some isozymes control pH homeostasis in tumors that appears to modulate the behaviour of cancer cells. CA XIII is the newest member of the CA gene family. It is a cytosolic isozyme which is expressed in a number of normal tissues. The present study was designed to investigate CA XIII expression in prospectively...
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