Article
Carbonic anhydrase XII functions in health and disease.
Gene - 5 Aug 2017
Waheed Abdul, Sly William S
Abstract excerpt
Human CAXII was initially identified as a cancer marker in different cancers and tumors. Expression of CAXII is regulated by hypoxia and estrogen receptors. CAXII expression has been also detected in several tissues, whereas in cancer and tumor tissues its expression is several fold higher. In brain tumors, an alternatively spliced form of CAXII is expressed. Higher expression of CAXII in breast cancer is...
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