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Article

Carbonic anhydrase XII is a new therapeutic target to overcome chemoresistance in cancer cells.

Oncotarget - 30 Mar 2015

Kopecka Joanna, Campia Ivana, Jacobs Andrea, Frei Andreas P, Ghigo Dario, Wollscheid Bernd, Riganti Chiara

Abstract excerpt

Multidrug resistance (MDR) in cancer cells is a challenging phenomenon often associated with P-glycoprotein (Pgp) surface expression. Finding new ways to bypass Pgp-mediated MDR still remains a daunting challenge towards the successful treatment of malignant neoplasms such as colorectal cancer.We applied the Cell Surface Capture technology to chemosensitive and chemoresistant human colon cancer to explore the...

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Source

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Identifiers

PMID: 25686827
DOI: 10.18632/oncotarget.2882
PMCID: PMC4466649

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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