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Article

Carbonic Anhydrase IX Inhibitors as Candidates for Combination Therapy of Solid Tumors

14 Dec 2021

Abstract excerpt

Combination therapy is becoming imperative for the treatment of many cancers, as it provides a higher chance of avoiding drug resistance and tumor recurrence. Among the resistance-conferring factors, the tumor microenvironment plays a major role, and therefore, represents a viable target for adjuvant therapeutic agents. Thus, hypoxia and extracellular acidosis are known to select for the most aggressive and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Identifiers

PMID: 34948200
DOI: 10.3390/ijms222413405

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