Article
Revealing Instability: Genetic Variation Underlies Variability in mESC Pluripotency.
Cell stem cell - 3 Sept 2020
D'Antonio Matteo, D'Antonio-Chronowska Agnieszka, Frazer Kelly A
Abstract excerpt
mESCs can self-renew indefinitely in vitro. However, depending on culture conditions some strains are more unstable than others. In this issue of Cell Stem Cell, Skelly et al. (2020) and Ortmann et al. (2020) shed light into the role genetic variation plays in control of ground state pluripotency.
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