Article
Variability in the generation of induced pluripotent stem cells: importance for disease modeling.
Stem cells translational medicine - 1 Sept 2012
Vitale Alejandra M, Matigian Nicholas A, Ravishankar Sugandha, Bellette Bernadette, Wood Stephen A, Wolvetang Ernst J, Mackay-Sim Alan
Abstract excerpt
In the field of disease modeling, induced pluripotent stem cells (iPSCs) have become an appealing choice, especially for diseases that do not have an animal model. They can be generated from patients with known clinical features and compared with cells from healthy controls to identify the biolog...
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