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Article

Variability in the generation of induced pluripotent stem cells: importance for disease modeling.

Stem cells translational medicine - 1 Sept 2012

Vitale Alejandra M, Matigian Nicholas A, Ravishankar Sugandha, Bellette Bernadette, Wood Stephen A, Wolvetang Ernst J, Mackay-Sim Alan

Abstract excerpt

In the field of disease modeling, induced pluripotent stem cells (iPSCs) have become an appealing choice, especially for diseases that do not have an animal model. They can be generated from patients with known clinical features and compared with cells from healthy controls to identify the biological bases of disease. This study was undertaken to determine the variability in iPSC lines derived from different...

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Identifiers

PMID: 23197870
DOI: 10.5966/sctm.2012-0043
PMCID: PMC3659735

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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