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Article

NS1-based DNA vaccination confers mouse protective immunity against ZIKV challenge.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Nov 2020

Zhan Ying, Pang Zheng, Du Yongping, Wang Wen, Yang Yang, Wang Wenling, Gao Gorge F, Huang Baoying, Deng Yao, Tan Wenjie

Abstract excerpt

The recent pandemic of Zika virus (ZIKV) infections highlight the urgent need for the development of a safe and efficacious ZIKV vaccine. We previously demonstrated that robust humoral and cellular immunity was elicited in BALB/c mice by ZIKV DNA vaccine encoding the precursor membrane (prM) and envelope (E) proteins while the protective efficacies were not evaluated against ZIKV challenge. To further explore the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32882433
DOI: 10.1016/j.meegid.2020.104521

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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