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Article

A single-dose plasmid-launched live-attenuated Zika vaccine induces protective immunity

7 Sept 2018

Abstract excerpt

BACKGROUND: Vaccines are the most effective means to fight and eradicate infectious diseases. Live-attenuated vaccines (LAV) usually have the advantages of single dose, rapid onset of immunity, and durable protection. DNA vaccines have the advantages of chemical stability, ease of production, and no cold chain requirement. The ability to combine the strengths of LAV and DNA vaccines may transform future vaccine...

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Identifiers

PMID: 30201444
DOI: 10.1016/j.ebiom.2018.08.056

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