Article
The CX3CL1-CX3CR1 system and psoriasis.
Experimental dermatology - 1 Nov 2006
Plant Darren, Young Helen S, Watson Rachel E B, Worthington Jane, Griffiths Christopher E M
Abstract excerpt
CX3CL1 is a chemoattractant and adhesion molecule that induces the redistribution of CX3CR1-positive inflammatory leucocytes to sites of inflammation. As a consequence of their increased expression in plaques of psoriasis, and location within genomic regions previously linked to this disease, CX3CL1, and its receptor CX3CR1, represent attractive positional and functional 'psoriasis susceptibility genes'. To...
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