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Article

The clonal evolution during long-term clinical course of multiple myeloma.

International journal of hematology - 1 Feb 2021

Mishima Yuko, Mishima Yuji, Shirouchi Yuko, Nishimura Noriko, Yokoyama Masahiro, Okabe Takashi, Inoue Norihito, Uryu Hideki, Fukuta Takanori, Hatake Kiyohiko, Terui Yasuhito

Abstract excerpt

Somatic gene mutations related to acceleration disease and clonal evolution in multiple myeloma strongly influence severe clinical outcomes. In this study, we traced the transition of somatic mutations during the clinical course of myeloma patients over a long-term follow-up period (8.5 year average). Seven myeloma cases treated with immuno-chemotherapy at our institution were analyzed with clinical courses and...

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Share to Cell Transformation, Neoplastic
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 32864713
DOI: 10.1007/s12185-020-02979-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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