Article
SLCO1B1 Gene Polymorphisms (rs2306283 and rs4149056) and Statin-Induced Myopathy in Jordanian Diabetics.
Current reviews in clinical and experimental pharmacology - 1 Jan 2021
Shahrure Zaineh M, Irshaid Yacoub M, Mustafa Khader N, Abujbara Mousa A, Al Shhab Mohammad, El-Khateeb Mohammed S, Ajlouni Kamel M
Abstract excerpt
BACKGROUND: The use of statins to lower high serum cholesterol levels may be associated with a number of adverse reactions, including severe myopathy. The solute carrier organic anion transporter 1B1 (SLCO1B1) gene, which encodes the organic anion-transporting polypeptide OATP1B1, is related to the intracellular transport of statins. The aim of this research was to study the association of rs2306283 and rs4149056...
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