Article
SLCO1B1 variants and statin-induced myopathy--a genomewide study.
The New England journal of medicine - 21 Aug 2008
Link E, Parish S, Armitage J, Bowman L, Heath S, Matsuda F, Gut I, Lathrop M, Collins R
Abstract excerpt
BACKGROUND: Lowering low-density lipoprotein cholesterol with statin therapy results in substantial reductions in cardiovascular events, and larger reductions in cholesterol may produce larger benefits. In rare cases, myopathy occurs in association with statin therapy, especially when the statins are administered at higher doses and with certain other medications. METHODS: We carried out a genomewide association...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.