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Article

Effect of SLCO1B1 gene polymorphisms and vitamin D on statin-induced myopathy.

Drug metabolism and personalized therapy - 28 Mar 2018

Alghalyini Baraa, El Shamieh Said, Salami Ali, Visvikis Siest Sophie, Fakhoury Hana M, Fakhoury Rajaa

Abstract excerpt

Background Statin therapy used to lower cholesterol levels results in a substantial reduction in cardiovascular complications. Previous observations in different ethnic populations showed that rs2306283A>G, p.Asn130Asp and rs4149056T>C, p.Val174Ala in solute carrier organic anion transporter 1B1 (SLCO1B1) gene encoding the organic transporter protein may be responsible for statin uptake, thus explaining the...

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PMID: 29420305
DOI: 10.1515/dmpt-2017-0030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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