Article
Association of the T130I Variant of the HNF4A Gene with Metabolic Syndrome and Its Components in Mexican Children.
Metabolic syndrome and related disorders - 1 Dec 2020
García-Rodríguez María Helena, Peña-Espinoza Barbara Itzel, de Los Angeles Granados-Silvestre María, Ortiz-López María Guadalupe, Menjivar Marta
Abstract excerpt
Background: Metabolic syndrome (MetS), a cluster of risk factors, leads to cardiovascular disease (CVD) and type 2 diabetes (T2D). The second leading cause of mortality in Mexico is T2D. Genetic factors participate in the pathogenesis of MetS. The HNFA gene encodes a transcription factor that plays a crucial role in energy homeostasis by regulating the metabolism of glucose and lipids. This study aimed to...
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