Article
Analysis of the contribution of FTO, NPC1, ENPP1, NEGR1, GNPDA2 and MC4R genes to obesity in Mexican children.
BMC medical genetics - 1 Feb 2013
Mejía-Benítez Aurora, Klünder-Klünder Miguel, Yengo Loic, Meyre David, Aradillas Celia, Cruz Esperanza, Pérez-Luque Elva, Malacara Juan Manuel, Garay Maria Eugenia, Peralta-Romero Jesús, Flores-Huerta Samuel, García-Mena Jaime, Froguel Philippe, Cruz Miguel, Bonnefond Amélie
Abstract excerpt
BACKGROUND: Recent genome wide association studies (GWAS) and previous positional linkage studies have identified more than 50 single nucleotide polymorphisms (SNPs) associated with obesity, mostly in Europeans. We aimed to assess the contribution of some of these SNPs to obesity risk and to the variation of related metabolic traits, in Mexican children. METHODS: The association of six European obesity-related...
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