Early-onset type 2 diabetes mellitus is associated to HNF4A T130I polymorphism in families of central Spain.

doi:10.1097/JIM.0000000000000114

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Article

Early-onset type 2 diabetes mellitus is associated to HNF4A T130I polymorphism in families of central Spain.

Journal of investigative medicine : the official publication of the American Federation for Clinical Research - 1 Dec 2014

Cieza-Borrella Clara, Díaz-Soto Gonzalo, Martínez-Pino Isabel, Puig-Domingo Manuel, González-Sarmiento Rogelio

Abstract excerpt

PURPOSE: Type 2 diabetes mellitus (type 2 DM) and maturity-onset diabetes of the young present some similar clinical and biochemical characteristics that make them difficult to differentiate. Currently, the polymorphism T130I (rs1800961) in the HNF4A (hepatocyte nuclear factor 4A) gene has been described as a risk factor to type 2 DM and shows an autosomal dominant inheritance pattern associated to β-cell...

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PMID: 25361053
DOI: 10.1097/JIM.0000000000000114

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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