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Article

Susceptibility background for type 2 diabetes in eleven Mexican Indigenous populations: HNF4A gene analysis.

Molecular genetics and genomics : MGG - 1 Dec 2017

Granados-Silvestre M A, Ortiz-López M G, Granados J, Canizales-Quinteros S, Peñaloza-Espinosa Rosenda I, Lechuga C, Acuña-Alonzo V, Sánchez-Pozos K, Menjivar M

Abstract excerpt

The genetic risk of developing type 2 diabetes (T2D) increases in parallel with the proportion of Native American ancestry. Mestizo Mexicans have a 70% Native Amerindian genetic background. The T130I polymorphism in the HNF4A gene has been associated with early-onset T2D in mestizo Mexicans. Thus, the aim of the present study was to evaluate the frequency and relationship of the T130I variant in the HNF4A gene...

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Identifiers

PMID: 28688048
DOI: 10.1007/s00438-017-1340-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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