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Article

Thr130Ile polymorphism of HNF4A gene is associated with gestational diabetes mellitus in Mexican population.

Journal of investigative medicine : the official publication of the American Federation for Clinical Research - 1 Mar 2014

Monroy Virginia Sánchez, Díaz César Antonio González, Trenado Lucila Maritza Lozano, Peralta José Manuel Campos, Soto Salvador Martín Polo

Abstract excerpt

Hepatocyte nuclear factor 4α (HNF4A) is a transcription factor that regulates the expression of genes in the liver, pancreas, kidney, intestine, and other tissues. Previous studies in the Mexican population have shown a high frequency of the Thr130Ile polymorphism and have suggested its important role in the pathogenesis of early-onset type 2 diabetes. The aim of the present study was to determine whether this...

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PMID: 24448600
DOI: 10.2310/JIM.0000000000000045

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Thr130Ile polymorphism of HNF4A gene is associated with gestational diabetes mellitus in Mexican population.PMID 24448600Read ↗

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