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Article

Common polymorphisms in MC4R and FTO genes are associated with BMI and metabolic indicators in Mexican children: Differences by sex and genetic ancestry.

Gene - 5 Sept 2020

López-Rodríguez Guadalupe, Estrada-Neria Alin, Suárez-Diéguez Teodoro, Tejero M Elizabeth, Fernández Juan Carlos, Galván Marcos

Abstract excerpt

BACKGROUND: Mexico is experiencing an epidemic of childhood obesity and overweight, the factors that determine type 2 diabetes and cardiovascular diseases. Even though variants in genes such as MC4R, LEP, LEPR, and FTO have been associated with the risk of obesity, in Mexico the level of miscegenation is heterogeneous, so this risk must be measured as genetic ancestry. This study aimed at evaluating the...

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Alpha-Ketoglutarate-Dependent Dioxygenase FTO
Body Mass Index
Ethnicity
Mexico
Overweight

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pediatric Obesity

Receptor, Melanocortin, Type 4

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PMID: 32505845
DOI: 10.1016/j.gene.2020.144840

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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