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Article

Prevalence of Somatic Mutations in Aldosterone-Producing Adenomas in Japanese Patients.

The Journal of clinical endocrinology and metabolism - 1 Nov 2020

Nanba Kazutaka, Yamazaki Yuto, Bick Nolan, Onodera Kei, Tezuka Yuta, Omata Kei, Ono Yoshikiyo, Blinder Amy R, Tomlins Scott A, Rainey William E, Satoh Fumitoshi, Sasano Hironobu

Abstract excerpt

CONTEXT: Results of previous studies demonstrated clear racial differences in the prevalence of somatic mutations among patients with aldosterone-producing adenoma (APA). For instance, those in East Asian countries have a high prevalence of somatic mutations in KCNJ5, whereas somatic mutations in other aldosterone-driving genes are rare. OBJECTIVES: To determine somatic mutation prevalence in Japanese APA...

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Identifiers

PMID: 32844168
DOI: 10.1210/clinem/dgaa595
PMCID: PMC7947976

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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