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Article

Prevalence and characterization of somatic mutations in Chinese aldosterone-producing adenoma patients.

Medicine - 1 Apr 2015

Wang Baojun, Li Xintao, Zhang Xu, Ma Xin, Chen Luyao, Zhang Yu, Lyu Xiangjun, Tang Yuzhe, Huang Qingbo, Gao Yu, Fan Yang, Ouyang Jinzhi

Abstract excerpt

Recently somatic mutations of KCNJ5, ATP1A1, ATP2B3, and CACNA1D have been identified in patients with aldosterone-producing adenoma (APA). The present study sequenced the DNA in the tissues and blood samples from Chinese patients with APA for KCNJ5, ATP1A1, ATP2B3, and CACNA1D gene mutations.Among the 114 patients, 86 (75.4%) were identified with KCNJ5 somatic mutations, including 3 previously reported (G151R,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25906099
DOI: 10.1097/MD.0000000000000708
PMCID: PMC4602684

Genes

KCNJ5

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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