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Article

Clinical characteristics of somatic mutations in Chinese patients with aldosterone-producing adenoma.

Hypertension (Dallas, Tex. : 1979) - 1 Mar 2015

Zheng Fang-Fang, Zhu Li-Min, Nie Ai-Fang, Li Xiao-Ying, Lin Jing-Rong, Zhang Ke, Chen Jing, Zhou Wen-Long, Shen Zhou-Jun, Zhu Yi-Chun, Wang Ji-Guang, Zhu Ding-Liang, Gao Ping-Jin

Abstract excerpt

Recent studies have shown that somatic mutations in the KCNJ5, ATP1A1, ATP2B3, and CACNA1D genes are associated with the pathogenesis of aldosterone-producing adenoma. Clinical profile and biochemical characteristics of the mutations in Chinese patients with aldosterone-producing adenoma remain unclear. In this study, we performed DNA sequencing in 168 Chinese patients with aldosterone-producing adenoma and found...

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Adrenal Cortex Neoplasms
Adrenocortical Adenoma
Aldosterone
Calcium Channels, L-Type
G Protein-Coupled Inwardly-Rectifying Potassium Channels

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Plasma Membrane Calcium-Transporting ATPases

Sodium-Potassium-Exchanging ATPase

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Identifiers

PMID: 25624344
DOI: 10.1161/HYPERTENSIONAHA.114.03346

Genes

KCNJ5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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