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Article

Biased signaling in naturally occurring mutations in human melanocortin-3 receptor gene.

International journal of biological sciences - 1 Jan 2015

Yang Fan, Huang Hui, Tao Ya-Xiong

Abstract excerpt

The melanocortin-3 receptor (MC3R) is primarily expressed in the hypothalamus and plays an important role in the regulation of energy homeostasis. Recently, some studies demonstrated that MC3R also signals through mitogen-activated protein kinases (MAPKs), especially extracellular signal-regulate...

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Identifiers

PMID: 25798062
DOI: 10.7150/ijbs.11032
PMCID: PMC4366641

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25798062-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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