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Article

FCER2: a pharmacogenetic basis for severe exacerbations in children with asthma.

The Journal of allergy and clinical immunology - 1 Dec 2007

Tantisira Kelan G, Silverman Eric S, Mariani Thomas J, Xu Jingsong, Richter Brent G, Klanderman Barbara J, Litonjua Augusto A, Lazarus Ross, Rosenwasser Lanny J, Fuhlbrigge Anne L, Weiss Scott T

Abstract excerpt

BACKGROUND: Although inhaled corticosteroids (ICSs) generally protect against severe exacerbations in asthma, they may result in elevated IgE levels, which are associated with exacerbations. OBJECTIVE: To determine whether variation in the low-affinity IgE receptor gene, FCER2, is associated with...

Read the complete abstract on PubMed

Topics

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Share to Administration, Inhalation
Share to Adrenal Cortex Hormones

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Asthma

Share to Immunoglobulin E

Share to Polymorphism, Single Nucleotide

Share to Receptors, IgE

Share to Severity of Illness Index

Source

Identifiers

PMID: 17980418
DOI: 10.1016/j.jaci.2007.09.005

Genes

FCER2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17980418-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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