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Article

SPEARS: Standard Performance Evaluation of Ancestral haplotype Reconstruction through Simulation.

Bioinformatics (Oxford, England) - 5 May 2021

Manching Heather, Wisser Randall J

Abstract excerpt

MOTIVATION: Ancestral haplotype maps provide useful information about genomic variation and insights into biological processes. Reconstructing the descendent haplotype structure of homologous chromosomes, particularly for large numbers of individuals, can help with characterizing the recombination landscape, elucidating genotype-to-phenotype relationships, improving genomic predictions and more. Inferring...

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PMID: 32840564
DOI: 10.1093/bioinformatics/btaa749
PMCID: PMC8097754

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