Article
hTERT, hTR and TERT promoter mutations as markers for urological cancers detection: A systematic review.
Urologic oncology - 1 Aug 2021
Morozov Andrey, Potoldykova Natalya, Chinenov Denis, Enikeev Mikhail, Glukhov Alexander, Shpikina Anastasia, Goryacheva Evgenia, Taratkin Mark, Malavaud Bernard, Enikeev Dmitry
Abstract excerpt
The clinical relevance of telomerase subunits (human reverse transcriptase - hTERT, and human telomerase RNA - hTR) and TERT promotor mutations as biomarkers in genitourinary cancers was reviewed through the systematic analysis of the current literature. We performed a systematic literature search using 2 databases (Medline and Scopus) over the past 20 years. Primary outcomes were sensitivity and specificity of...
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