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Article

Non-invasive prediction of recurrence in bladder cancer by detecting somatic TERT promoter mutations in urine.

British journal of cancer - 8 Aug 2017

Descotes Françoise, Kara Norelyakin, Decaussin-Petrucci Myriam, Piaton Eric, Geiguer Florence, Rodriguez-Lafrasse Claire, Terrier Jean E, Lopez Jonathan, Ruffion Alain

Abstract excerpt

BACKGROUND: Urothelial bladder cancer (UBC) is characterised by a high risk of recurrence. Patient monitoring is currently based on iterative cystoscopy and on urine cytology with low sensitivity in non-muscle-invasive bladder cancer (NMIBC). Telomerase reverse transcriptase (TERT) is frequently reactivated in UBC by promoter mutations. METHODS: We studied whether detection of TERT mutation in urine could be a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28683471
DOI: 10.1038/bjc.2017.210
PMCID: PMC5558690

Genes

TERT
UBC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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