Article
Parathyroid Hormone and Bone Mineral Density: A Mendelian Randomization Study.
The Journal of clinical endocrinology and metabolism - 1 Nov 2020
Qu Zihao, Yang Fangkun, Hong Jianqiao, Wang Wei, Yan Shigui
Abstract excerpt
PURPOSE: Accumulating evidence implicates parathyroid hormone (PTH) in the development of osteoporosis. However, the causal effect of PTH on bone mineral density (BMD) remains unclear. Thus, this study is aimed at exploring the association between the concentrations of serum PTH and BMD. METHODS: The instrumental variables for PTH were selected from a large-scale genome-wide association study (GWAS; n = 29 155)....
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