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Impact of serum calcium levels on total body bone mineral density: A mendelian randomization study in five age strata.

Clinical nutrition (Edinburgh, Scotland) - 1 May 2021

Sun Jing-Yi, Zhang Haihua, Zhang Yan, Wang Longcai, Sun Bao-Liang, Gao Feng, Liu Guiyou

Abstract excerpt

BACKGROUND & AIMS: Mendelian randomization (MR) studies have reported the causal association between serum calcium levels and bone mineral density (BMD). The results showed that genetically increased serum calcium levels in individuals with normal calcium levels did not increase BMD and could even reduce BMD. However, whether there are differences in the association between serum calcium and BMD in different age...

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PMID: 33933738
DOI: 10.1016/j.clnu.2021.03.012

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