Article
Epigenetic mechanisms and therapeutic advances in diffuse midline glioma (Review).
Oncology reports - 1 Mar 2026
Wu Wenbo, Chen Wenlin, Ma Wenbin, Wang Yu
Abstract excerpt
Gliomas are the most common primary malignant tumors of the central nervous system in adults, with diffuse midline gliomas (DMG) being particularly aggressive and associated with inferior survival rate. Notwithstanding advances in molecular diagnostics and epigenetics, the specific pathological mechanisms of DMG remain to be fully elucidated. A series of studies have demonstrated that histone modifications,...
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