Article
Applications of Functional Genomics for Drug Discovery.
SLAS discovery : advancing life sciences R & D - 1 Sept 2020
Kabadi Ami, McDonnell Eoin, Frank Christopher L, Drowley Lauren
Abstract excerpt
Many diseases, such as diabetes, autoimmune diseases, cancer, and neurological disorders, are caused by a dysregulation of a complex interplay of genes. Genome-wide association studies have identified thousands of disease-linked polymorphisms in the human population. However, detailing the causative gene expression or functional changes underlying those associations has been elusive in many cases. Functional...
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