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Article

Is it a new culprit? "TERT promoter mutation" in an aggressive pediatric pilocytic astrocytoma.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery - 1 Mar 2021

Francis Jacintha Vikeneswary, Tanrıkulu Bahattin, Danyeli Ayca Ersen, Özek M Memet

Abstract excerpt

Recent advances in the genomic study have revolutionized the discovery of molecular biomarkers in glioma not only to aid in targeted therapy but also to prognosticate character of tumor and outcome of a patient.The usually benign nature of pilocytic astrocytoma (PA) can now be challenged with the discovery of genomic alterations that could promote more aggressive clinical behavior. CDKN2A deletion and ATRX gene...

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Identifiers

PMID: 32813054
DOI: 10.1007/s00381-020-04803-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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