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Biology and grading of pleomorphic xanthoastrocytoma—what have we learned about it?

3 Jul 2020

Abstract excerpt

Pleomorphic xanthoastrocytoma (PXA) is a rare astrocytoma predominantly affecting children and young adults. We performed comprehensive genomic characterization on a cohort of 67 patients with histologically defined PXA (n = 53, 79%) or anaplastic PXA (A-PXA, n = 14, 21%), including copy number analysis (ThermoFisher Oncoscan, n = 67), methylation profiling (Illumina EPIC array, n = 43) and targeted next...

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PMID: 32619305
DOI: 10.1111/bpa.12874

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