Article
Leukemic stem cell phenotype is associated with mutational profile in acute myeloid leukemia.
The Korean journal of internal medicine - 1 Mar 2021
Han Heejoo, Byun Ja Min, Shin Dong-Yeop, Yoon Sung-Soo, Koh Youngil, Hong Junshik, Kim Inho, Lee Chansup, Yoo Hyeonjoo, Yun Hongseok, Kim Man Jin, Cho Sung Im, Seong Moon-Woo, Park Sung Sup
Abstract excerpt
BACKGROUND/AIMS: Understanding leukemic stem cell (LSC) is important for acute myeloid leukemia (AML) treatment. However, association of LSC with patient prognosis and genetic information in AML patients is unclear. METHODS: Here we investigated the associations between genetic information and the various LSC phenotypes, namely multipotent progenitor (MPP)-like, lymphoid primed multipotent progenitor (LMPP)-like...
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