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Review Cancer stem cells in haematological malignancies

1 Jan 2015

Abstract excerpt

At least several types of human haematological malignancies can now be seen as 'stem-cell diseases'. The best-studied in this context is acute myeloid leukaemia (AML). It has been shown that these diseases are driven by a pool of 'leukaemia stem cells (LSC)', which remain in the quiescent state, have the capacity to survive and self-renew, and are responsible for the recurrence of cancer after classical...

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PMID: 25691816
DOI: 10.5114/wo.2014.47127

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