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Analyzing the Metabolic Phenotype of Bone Marrow-Derived Dendritic Cells by Assessing Their Oxygen Consumption and Extracellular Acidification.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2020

Wei Hsi-Ju, Letterio John J, Pareek Tej K

Abstract excerpt

Dendritic cells (DCs) are the bridge between innate and T cell-dependent adaptive immunity, and are promising therapeutic targets for cancer and immune-mediated disorders. In the recent past, DCs have gained significant interest to manipulate them for the treatment of cancer and immune-mediated disorders. This can be achieved by differentiating them into either immunogenic or tolerogenic DCs (TolDCs), by...

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PMID: 32808226
DOI: 10.1007/978-1-0716-0802-9_13

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