Article
Biochemical Underpinnings of Immune Cell Metabolic Phenotypes.
Immunity - 16 May 2017
Olenchock Benjamin A, Rathmell Jeffrey C, Vander Heiden Matthew G
Abstract excerpt
The metabolism of immune cells affects their function and influences host immunity. This review explores how immune cell metabolic phenotypes reflect biochemical dependencies and highlights evidence that both the metabolic state of immune cells and nutrient availability can alter immune responses. The central importance of oxygen, energetics, and redox homeostasis in immune cell metabolism, and how these factors...
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