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Article

Dysregulated metabolism: A friend-to-foe skewer of macrophages.

International reviews of immunology - 1 Jan 2023

Mortezaee Keywan, Majidpoor Jamal

Abstract excerpt

Metabolic reprogramming is a hallmark of solid cancers. Macrophages as major constituents of immune system take important roles in regulation of tumorigenesis. Pro-tumor M2 macrophages preferentially use oxidative phosphorylation (OXPHOS) to meet their metabolic demands, while anti-tumor M1 macrophages use glycolysis as their dominant metabolic source. Dysregulation in metabolic systems is a driving force of...

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PMID: 35792727
DOI: 10.1080/08830185.2022.2095374

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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