Heterogeneity of fetal hemoglobin production in adult red blood cells

doi:10.1097/moh.0000000000000640

Article

Heterogeneity of fetal hemoglobin production in adult red blood cells

23 Feb 2021

Abstract excerpt

PURPOSE OF REVIEW: Small amounts of fetal hemoglobin can be expressed in a subset of adult red blood cells called F-cells. This review examines the potential mechanisms and clinical implications of the heterogeneity of fetal hemoglobin expression. RECENT FINDINGS: Although the heterocellular nature of fetal hemoglobin expression in adult red blood cells has been noted for over 70 years, the molecular basis of...

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