Article
GPR56: An adhesion GPCR involved in brain development, neurological disorders and cancer.
Brain research - 15 Nov 2020
Ganesh Raksha A, Venkataraman Krishnan, Sirdeshmukh Ravi
Abstract excerpt
GPR56/ADGRG1 is a member of the adhesion G-protein coupled receptor (aGPCR) family and one of the important players in the normal development of the brain. It plays a pivotal role in the diverse neurobiological processes, including cortical formation, oligodendrocyte development, and myelination. Mutations in GPR56 are known to cause brain malformation, myelination defects and are also implied in many cancers,...
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